With the holiday season just around the corner and 2020 being what it has been, here at The PotNetwork we thought we would take a look back at one of our classic pieces on the benefits of medical marijuana. Here, you’ll learn what medical cannabis is, what it treats, and best of all, how you can find some of your own.
So, if 2020 has been stressing you out (and really, who hasn;t been stressed out this year), don’t worry. Sit back and learn how medical cannabis can help you, from one of our classic stories, “What Are The Benefits of Medical Marijuana?”
What Are The Benefits of Medical Marijuana?
Cannabinoids are one of the most highly studied compounds in the world today. That includes both endocannabinoids — those produced naturally by our own bodies — and phytocannabinoids — those produced in medical marijuana and phytocannabinoid-rich hemp. What are those studies telling us?
The variety of claims being made about the medicinal benefits of marijuana and the role of the human endocannabinoid system (ECS) in human health runs deep and wide. Not only do proponents claim that phytocannabinoids have powerful effects on our ECS such as the regulation of mood and pain, there are also claims that it has effects which are entirely independent of the ECS, such as that it can act as an antibiotic, an anti-inflammatory agent, an antioxidant, a neuroprotectant, and more. It seems the only thing that proponents aren’t claiming is that cannabinoids can be used to clean the kitchen sink.
Is this possible? Does medical marijuana produce this wide range of effects on the human body? Or is all this talk to be considered “snake oil” marketing? Should we file these medical claims under the heading “too good to be true”? And if most of these claims are, indeed, true, what physiological mechanisms might account for the cornucopia of medicinal effects provided by phytocannabinoids?
The Research Behind Medical Marijuana
If there were only a small handful of studies on the medical benefits of phytocannabinoids, these claims could be easily dismissed. However, there are more than just a few studies which suggest that phytocannabinoids do, indeed, provide this wide range of health benefits.
It’s important to understand that researchers do not undertake lab or clinical studies to determine the effects of compounds such as phytocannabinoids randomly. For a study to be funded, researchers must provide a reasonable hypothesis and sufficient evidence to convince various institutions that it will be well worth investing money into funding these research studies. And not just a few of these studies get funded. Scores of studies have been undertaken, and scores more are underway to determine the medicinal benefits of phytocannabinoids as well as other compounds found in medical marijuana.
Not only do well-respected scientists and medical professionals from clinics, hospitals, research centers and universities all over the world believe that the medicinal benefits of marijuana and its derivatives are very real, a majority of state lawmakers, too, have looked at the evidence and made the decision that the evidence is powerful enough that entire regulatory systems should be implemented to allow the use of medical marijuana by patients in their states. And many federal lawmakers, too, are coming to the same conclusion.
A Growing Base of Support
According to a list compiled by NORML, the National Organization for the Reform of Marijuana Laws, a leading voice in the pro-medical marijuana movement for nearly 50 years, more than 60 U.S. and international health organizations support the use of medical marijuana for the treatment of a wide variety of conditions. These include several well-respected institutions such as the American Cancer Society and the American Medical Association, the National Academy of Sciences Institute Of Medicine, and the National Association for Public Health Policy.
[Read More: What Are The Benefits of Medical Marijuana?]
The Substance Abuse and Mental Health Services Administration (SAMHSA) maintains a database of deaths attributed to the use of pharmaceuticals. As testimony to the safety of medical marijuana, a report published by the group entitled, “The Drug Awareness Warning Network Annual Report,” claims that there are no records of death attributable to its use in medicine.
The Benefits of Medical Marijuana
Non-profit medical cannabis information source ProjectCBD.org maintains a comprehensive list of research studies into the efficacy of medical marijuana. Some of these studies are done on lab animals. Some are done on cell lines in Petri dishes and test tubes. Some are done with human subjects. And some present data gathered in polls and surveys of medical cannabis users.
Below is a sampling of some select research papers which suggest that medical marijuana shows promise as a therapeutic agent in the treatment of a wide variety of ailments.
Medical Marijuana Reduces Inflammation
Cannabinoids are widely known to help reduce a variety of forms of inflammation which are indicated in a wide range of conditions including the most common causes of death such atherosclerosis, heart disease, angina, arthritis, kidney disease, and liver disease.
- The role of the endocannabinoid system in atherosclerosis
- Cannabinoid receptors in atherosclerosis
- The potential use of cannabidiol in the therapy of metabolic syndrome
- The endocannabinoid system: an emerging key player in inflammation
- Cannabinoids, endocannabinoids, and related analogs in inflammation
- Study: History Of Cannabis Use Associated With Increased Survival Rates Among Heart Attack Patients
- Cannabinoids and the kidney: effects in health and disease.
- The endocannabinoid system and liver diseases
- Potential of CBD for the Treatment of Viral Hepatitis
Medical Marijuana Reduces Pain
Medical marijuana and CBD oil are widely used for the reduction of a variety of types of pain including arthritis pain, migraines, fibromyalgia, rheumatism, angina, and much more.
- Cannabis use in patients with fibromyalgia
- Cannabinoids for fibromyalgia
- Cannabinoids and hallucinogens for headache
- The endocannabinoid system and migraine
- Cannabinoids suitable for migraine prevention
- Cannabis, pain, and sleep: Sativex Clinical Trials
- Cannabinoids for neuropathic pain
- Cannabinoids in the management of difficult to treat pain
- Marijuana extract helps prevent chemo pain
- Pot users less likely to take painkillers
- CBD & THC interactions on acute pain and locomotor activity
Medical Marijuana Treats Mood Disorders
Some of the mood disorders for which medical marijuana and CBD oil are commonly used include anxiety, depression, PTSD, and OCD.
- CBD as an anxiolytic drug
- CBD reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients
- Endocannabinoid system dysfunction in mood and related disorders
- Antidepressant-Like and Anxiolytic-Like Effects of CBD
- The endocannabinoid system and the treatment of mood and anxiety disorders
- The endocannabinoid system & the treatment of mood and anxiety disorders
- The endocannabinoid system & psychiatric disorders
- Endocannabinoid system dysfunction in mood and related disorders
- Effects of CBD on regional cerebral blood flow
- Cannabidiol, neuroprotection and neuropsychiatric disorders
- Therapeutic Potential of Cannabinoids in Psychosis
Medical Marijuana Reduces Epilepsy, Seizures, Spasms
Numerous forms of epilepsy, as well as disorders involving involuntary movements such as Parkinson’s Disease, Huntington’s Disease, and Tourette Syndrome, are successfully being treated with medical marijuana and CBD oil.
- Cannabis and amyotrophic lateral sclerosis
- Cannabinoids: Novel medicines for the treatment of Huntington’s disease
- Controlled clinical trial of cannabidiol in Huntington’s disease
- Neurological aspects of medical use of CBD
- THC & CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
- CBD/THC Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice
- Neurological aspects of medical use of CBD
Medical Marijuana Treats Skin Conditions
Cannabinoid-based oral and topical medications have been shown to help reduce symptoms of skin conditions such as psoriasis, eczema, rashes, itching, and allergic reactions.
- CBD exerts sebostatic and anti-inflammatory effects on human sebocytes
- The endocannabinoid system of the skin in health and disease
- Epigenetic control of skin differentiation genes by phytocannabinoids
- Attenuation of allergic contact dermatitis through the endocannabinoid system
- The role of cannabinoids in dermatology
Medical Marijuana Helps With Sleep Issues
Medical marijuana and CBD oil are widely used by patients with sleep disorders such as insomnia, not only helping people get to sleep but to enjoy more restful sleep.
- The nonpsychoactive Cannabis constituent cannabidiol is a wake-inducing agent
- Cannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex
- Effects of acute systemic administration of CBD on sleep-wake cycle in rats
- CBD modulates sleep in rats
- Endocannabinoid modulation of cortical up-states and NREM sleep
- Endocannabinoid Signaling Regulates Sleep Stability
- Cannabis, Cannabinoids, and Sleep: a Review of the Literature
Medical Marijuana Reduces Digestive Issues
Crohn's disease, colitis, IBS, ulcers, diarrhea, constipation, and nausea are just some of the digestion-related conditions which are known to respond well to treatment with medical marijuana and CBD oil.
- CBD in inflammatory bowel diseases: a brief overview
- Cannabis finds its way into treatment of Crohn’s disease
- Cannabinoids and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- Cannabinoids and gastrointestinal motility: Animal and human studies
- Manipulation of the Endocannabinoid System in Colitis: A Comprehensive Review
- Cannabidiol in inflammatory bowel diseases: A brief overview
- CBD and the gut: New developments and emerging concepts
- Endocannabinoids and the gastrointestinal tract
- Getting into the weed: the role of the endocannabinoid system in the brain-gut axis
- Cannabidiol in inflammatory bowel diseases: A brief overview
- Regulation of nausea and vomiting by cannabinoids
Medical Marijuana and Neuroprotection
Patients with brain conditions such as Alzheimer’s disease and dementia are among the common conditions which qualify patients for state medical marijuana programs.
- The therapeutic potential of the endocannabinoid system for Alzheimer’s disease
- Endocannabinoid signaling in Alzheimer’s disease
- Molecular Targets of Cannabidiol in Neurological Disorders
- CBD: A promising drug for neurodegenerative disorders?
- Cannabidiol, neuroprotection and neuropsychiatric disorders
- Neurological aspects of medical use of CBD
- Cannabidiol for the treatment of psychosis in Parkinson’s disease
- Therapeutic potential of cannabinoids in CNS disease
- Neurological aspects of medical use of CBD
Medical Marijuana Treats Psychological Disorders
Medical marijuana is widely believed to be beneficial for the treatment of conditions such as ADHD, autism, addiction, anorexia, bipolar disorder, schizophrenia, and others.
- Endocannabinoid Signaling in Autism
- The endocannabinoid system and extinction learning
- The Use of Medicinal Marijuana for Posttraumatic Stress Disorder: A Review
- Cannabis Drug Shows Promise in Treating Schizophrenia
- CBD as an antipsychotic drug
- Cannabidiol as a potential treatment for psychosis
- Medical use of cannabis. CBD: A new light for schizophrenia?
- Cannabinoids and schizophrenia
- Antipsychotic-like effects of cannabidiol and rimonabant
- CBD monotherapy for treatment-resistant schizophrenia
- Cannabis with high CBD content is associated with fewer psychotic experiences
- Marijuana compound treats schizophrenia with few side effects: Clinical trial
Medical Marijuana Prevents or Reduces Tumors
Although this benefit is more controversial than others, research done on cancerous cell lines as well as studies performed on animals suggest that cannabinoids found in medical marijuana and cannabinoid-rich hemp can induce a process known as apoptosis, which forces cancerous cells to “commit suicide.”
- CBD as potential anticancer drug
- CBD inhibits angiogenesis by multiple mechanisms
- The inhibitory effects of CBD on systemic malignant tumors
- Marijuana fights cancer and helps manage side effects
- The Influence of Biomechanical Properties and Cannabinoids on Tumor Invasion
- Cannabinoids - a new weapon against cancer?
Medical Marijuana Regulates Blood Sugar
Cannabinoids have been shown to play a role in the body’s ability to regulate blood sugar levels and prevent, delay, or treat diabetes.
- The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- CBD lowers incidence of diabetes in non-obese diabetic mice
- The endocannabinoid system in obesity and type 2 diabetes
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
- The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
Medical Marijuana In Conclusion
Is the wide range of medical benefits of marijuana and hemp “too good to be true,” simply the result of greedy con artists hoping to take advantage of medical patients for their own financial gain, or ‘potheads’ just trying to find ways to get marijuana legalized? As you can see, thousands of research scientists, medical and healthcare professionals, lawmakers, and patient advocates will tell you, “no,” it’s not too good to be true. The medical benefits of marijuana, while not a miracle cure, are both good and true.